Wang AZ, Mashimo BL^#, Schaettler MO^#, Sherpa ND, Leavitt LA, Livingstone AJ, Khan SM, Li M, Anzaldua-Campos M, Bradley JD, Leuthardt EC, Kim AH, Dowling JL, Chicoine MR, Jones PS, Choi BD, Cahill DP, Carter BS, Petti AA^{^}, Johanns TM^{^}, Dunn GP^{^}. Glioblastoma-infiltrating CD8+ T cells are predominantly a clonally expanded GZMK+ effector population [Internet]. bioRxiv. 2023 p. 2023.08.25.554678; Available from: https://www.biorxiv.org/content/10.1101/2023.08.25.554678v1

Published in Cancer Discov. 2024 Jun 3;14(6):1106-1131. doi: 10.1158/2159-8290.CD-23-0913.PMID: 38416133

Schaettler MO, Desai R, Wang AZ, Livingstone AJ, Kobayashi DK, Coxon AT, Bowman-Kirigin JA, Liu CJ, Li M, Bender DE, White MJ, Kranz DM, Johanns TM, Dunn GP. TCR-engineered adoptive cell therapy effectively treats intracranial murine glioblastoma. J Immunother Cancer. 2023 Feb;11(2):e006121. doi: 10.1136/jitc-2022-006121. PMID: 36808076; PMCID: PMC9944319.

Khan SM^#, Desai R^#, Coxon A, Livingstone A, Dunn GP, Petti A, Johanns TM. Impact of CD4 T cells on intratumoral CD8 T-cell exhaustion and responsiveness to PD-1 blockade therapy in mouse brain tumors. J Immunother Cancer. 2022 Dec;10(12):e005293. doi: 10.1136/jitc-2022-005293. PMID: 36543376; PMCID: PMC9772691.

Bowman-Kirigin JA, Desai R, Saunders BT, Wang AZ, Schaettler MO, Liu CJ, Livingstone AJ, Kobayashi DK, Durai V, Kretzer NM, Zipfel GJ, Leuthardt EC, Osbun JW, Chicoine MR, Kim AH, Murphy KM, Johanns TM, Zinselmeyer BH, Dunn GP. The Conventional Dendritic Cell 1 Subset Primes CD8+ T Cells and Traffics Tumor Antigen to Drive Antitumor Immunity in the Brain. Cancer Immunol Res. 2023 Jan 3;11(1):20-37. doi: 10.1158/2326-6066.CIR-22-0098. PMID: 36409838.

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